Severe Hyperparathyroidism with Secondary Osteitis Fibrosa Cystica and Brown Tumors Mimicking Bone Metastasis
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چکیده
منابع مشابه
Severe Hyperparathyroidism with Secondary Osteitis Fibrosa Cystica and Brown Tumors Mimicking Bone Metastasis
Introduction: The classical presentation of primary hyperparathyroidism, osteitis fibrosa cystica, has become very rare nowadays. This rarity makes it sometimes misdiagnosed leading to disastrous outcomes. Methods: We present a case of an undiagnosed primary hyperparathyroidism with severe osteitis fibrosa cystica and brown tumors that was first misdiagnosed as having bone metastasis. Conclusio...
متن کامل[Primary hyperparathyroidism with osteitis fibrosa cystica mimicking a malignant bone tumor].
The most common clinical presentation of primary hyperparathyroidism (PHP) is asymptomatic hypercalcemia, and diagnosis of PHP based on the presence of bone manifestations such as osteitis fibrosa cystica (OFC) is increasingly uncommon. OFC occurs in less than 5% of patients with PHP and suggests a more severe or long-standing disease. OFC is characterized by the occurrence of bone pain associa...
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Although bone disease and stone disease are the universally accepted classical manifestations of primary hyperparathyroidism, clinical parathyroid bone disease is rarely seen today in the United States (<5% of patients) and Western Europe. Nevertheless, in a given patient, classical skeletal involvement can be the first sign of primary hyperparathyroidism, but not recognized because it is not u...
متن کاملSpontaneous healing of osteitis fibrosa cystica in primary hyperparathyroidism.
A 24-year-old man with primary hyperparathyroidism and osteitis fibrosa cystica developed acute hypocalcaemia. Spontaneous healing of his bone disease was confirmed radiographically and by correction of the serum alkaline phosphatase. Hypercalcaemia associated with a raised serum parathyroid hormone recurred 90 weeks after the initial presentation. During the fourth neck exploration a parathyro...
متن کاملSuccessful Treatment of Osteitis Fibrosa Cystica from Primary Hyperparathyroidism
Osteitis Fibrosa Cystica (OFC) is defined as the classic skeletal manifestation of advanced primary hyperparathyroidism. With the increased detection by means of routine calcium screening, the clinical profile of primary hyperparathyroidism in Western countries has shifted from symptomatic disease to one with subtle or no specific symptoms ("asymptomatic" primary hyperparathyroidism). The autho...
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ژورنال
عنوان ژورنال: Endocrinology & Metabolic Syndrome
سال: 2016
ISSN: 2161-1017
DOI: 10.4172/2161-1017.1000245